Encephalitis, also known as brain inflammation, can be caused by a variety of factors, including bacterial, fungal, and viral infections, as well as autoimmune responses in which the immune system targets brain tissue.
The symptoms of encephalitis vary widely, depending on the underlying cause. Typical symptoms include fever, intense headaches, seizures, altered consciousness, confusion, motor difficulties, and speech impairments. Viral encephalitis is specifically defined as brain inflammation caused by viral infections. It's crucial to identify the viruses that can lead to brain inflammation and learn how to recognize their symptoms.
Viral infections that may result in brain inflammation
There are several types of viral infections that can cause inflammation of the brain, including:
Herpes simplex virus (HSV)
Herpes simplex virus (HSV) is divided into two types, HSV-1 and HSV-2, both of which can lead to encephalitis. HSV-1 is commonly associated with oral blisters, whereas HSV-2 is linked to genital herpes.
Although HSV-1 encephalitis is uncommon, it can be a severe condition that results in brain damage and even death. Administering antiviral medications is crucial to minimizing the risk of brain damage in such cases.
Other herpes viruses
Other herpes viruses, like Epstein-Barr virus (EBV) and Varicella-Zoster virus (VZV), can also lead to brain inflammation. EBV is commonly linked to infectious mononucleosis, characterized by symptoms such as high fever, swollen lymph nodes, sore throat, extreme fatigue, and an enlarged spleen.
Varicella-Zoster virus typically causes chickenpox during childhood. Even after recovery from chickenpox, the virus remains dormant in the body. It can resurface later in life as shingles, which is characterized by a painful skin rash accompanied by burning or itching.
Read more: What Is Brain Inflammation (Encephalitis) Like Caused By The Nipah Virus?
Enterovirus
Enteroviruses constitute a cluster of viruses that target the gastrointestinal system and can induce a spectrum of symptoms, spanning from mild to severe. Although most infections are mild, they can pose serious risks to individuals with compromised immune systems.
Enteroviruses have the potential to trigger central nervous system (CNS) infections, leading to inflammation in the brain and spinal cord. This condition is highly severe and could be life-threatening. The infection may interfere with the regular functioning of the brain and nervous system, manifesting symptoms such as high fever, intense headaches, seizures, impaired consciousness, and other neurological impairments.
Encephalitis caused by mosquitoes
Mosquito-borne infections like West Nile Virus, La Crosse Virus, St. Louis Encephalitis Virus, and Western Equine Encephalitis Virus are capable of triggering brain inflammation in humans. The symptoms range widely, encompassing fever, headache, fatigue, and various neurological manifestations like seizures, confusion, and paralysis.
These viral infections' symptoms can manifest anywhere from days to weeks after exposure to the mosquito-borne virus. In severe instances, the infection can advance to cause significant encephalitis or meningitis.
Read more: When Need To Get Rabies Vaccine (VAR) And Anti Rabies Serum (SAR)?
Rabies
The rabies virus can lead to a rare yet severe form of encephalitis. This infection typically spreads through a bite or wound contaminated with the saliva of an infected animal, particularly dogs, cats, or wild animals like foxes, raccoons, and bats.
Following infection, the rabies virus often advances swiftly, reaching the central nervous system and causing inflammation of the brain and spinal cord, known as rabies encephalitis.
Initially, rabies symptoms resemble those of the flu, including fever, headache, fatigue, and itching or burning at the site of the bite. As the infection progresses, symptoms intensify and may include confusion, restlessness, difficulty swallowing, seizures, mental disturbances, and paralysis. Without immediate treatment, rabies can be fatal, leading to death.
Preventing encephalitis caused by viruses involves vaccination, avoiding contact with infected animals, practicing hygiene, environmental awareness, and protecting oneself when traveling. Once symptoms of infection appear, see a doctor immediately for treatment.
If you need medical advice or consultation, you can either visit a doctor or make use of the consultation features that are available in the Ai Care application by downloading the Ai Care application from the App Store or Play Store.
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- dr. Monica Salim
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John E. Greenlee, MD (2022). Rabies. Available from: https://www.msdmanuals.com/professional/neurologic-disorders/brain-infections/rabies