Mpox (monkeypox) is a zoonotic disease caused by the monkeypox virus. Vaccination is a key measure to prevent this disease.

In Indonesia, the MVA-BN vaccine is one of the vaccines available to protect the population from the spread of the Mpox virus. Learn more about the MVA-BN vaccine and when it’s necessary.

What is the MVA-BN Vaccine?

The MVA-BN (Modified Vaccinia Ankara-Bavarian Nordic) vaccine was initially developed to combat the smallpox virus. Created by the biotechnology company Bavarian Nordic, this vaccine is also known to effectively protect against the Mpox virus, which belongs to the same viral family as smallpox.

The MVA-BN vaccine contains a weakened version of the vaccinia virus. This weakened virus cannot reproduce within the human body but can still stimulate an immune response.

The MVA-BN vaccine is particularly safe due to its inability to replicate in the body, minimizing the risk of severe side effects.

Moreover, this vaccine has received approval from various health authorities, including the United States Food and Drug Administration (FDA), the European Medicines Agency (EMA), and Indonesia’s Food and Drug Administration (BPOM).

How the MVA-BN Vaccine Works

The MVA-BN vaccine prompts the immune system to recognize and fight viruses related to smallpox and Mpox. Once injected, the weakened viruses activate an immune response without causing an actual infection.

This immune response helps the body produce antibodies and immune cells that can recognize and defend against smallpox and Mpox viruses if exposed in the future.

While the vaccine does not provide 100% immunity, its ability to reduce the severity of disease is highly significant, especially for individuals at high risk of complications or those with weakened immune systems.

Side Effects and Safety of the MVA-BN Vaccine

Like most vaccines, the MVA-BN vaccine can cause mild side effects, such as:

• Pain at the injection site
• Headache
• Mild fever
• Fatigue

Since the virus in the vaccine cannot replicate, serious side effects are rare. It is even considered safe for people with compromised immune systems.

Who Can Get the MVA-BN Vaccine?

In Indonesia, the MVA-BN vaccine is available on a limited basis. It is not given to the general population but is recommended for individuals at higher risk of Mpox infection.

The following groups are prioritized for the MVA-BN vaccine:

Health workers

Healthcare professionals who treat Mpox patients or work in facilities that manage Mpox cases are advised to get the MVA-BN vaccine due to their elevated risk of exposure.

Close contact with the Mpox cases

Those in close contact with individuals infected with Mpox are encouraged to receive the vaccine to help prevent serious infections or complications.

Laboratory workers

Lab personnel working with samples that may contain the Mpox virus are also advised to get vaccinated.

If you belong to one of these high-risk groups, it's recommended that you contact your nearest healthcare facility. You can also consult with a doctor about Mpox infections through the Ai Care app, available on the App Store or Play Store.

Looking for more information on other diseases? Click here!