Multiple Sclerosis (MS) is not a common disease, but it is also not rare. It is known as "the disease of a thousand faces" because the symptoms are so diverse and can differ from person to person. In fact, MS symptoms can vary over time.
Multiple sclerosis is difficult to diagnose and treat due to its diverse range of symptoms. What type of disease is multiple sclerosis?
What is multiple sclerosis and its causes?
Multiple sclerosis (MS) is an autoimmune disease. This central nervous system disease affects the brain, spinal cord, and occasionally the optic nerve. MS patients have an immune system that mistakenly attacks the protective coating (myelin) that surrounds nerve fibers. Myelin acts as insulation for electrical wires, smoothing the electrical signals that travel between the brain, spinal cord, and the rest of the body.
The damage to myelin caused by the immune system's erroneous attack disrupts electrical signals, resulting in a breakdown in communication between the brain and body and producing MS symptoms.
MS's causes are not fully understood, but there are several factors that contribute to an increased risk of developing this condition:
Demyelination
The main cause of MS is demyelination, which destroys myelin and disrupts the nerves' ability to transmit messages to one another. Without healthy myelin, nerve signals are disrupted, causing MS symptoms.
Smoking
Smoking has been linked to an increased risk of developing MS and may accelerate the disease's progression once diagnosed.
Toxic Exposure
Exposure to environmental toxins, such as secondhand smoke and pesticides, may increase the risk of MS. Certain chemicals may trigger an autoimmune response that damages myelin.
Low levels of vitamin D
Vitamin D regulates immune system function. Low exposure to sunlight, which produces vitamin D, is linked to an increased risk of MS.
Viral exposure
People who are susceptible to MS may develop an autoimmune response after being exposed to viruses such as the Epstein-Barr virus. Other studies suggest that other viral infections contribute to the development of MS, but this relationship is not fully understood. More research is needed in this area.
Childhood obesity
Obesity, particularly in childhood and adolescence, may raise the risk of MS. Obesity impairs the immune system and causes inflammation, which contributes to a variety of diseases, including MS.
Genetic predisposition
Having a close family member with MS increases the likelihood of developing the disease. Although MS is not directly inherited, certain genetic predispositions can increase one's susceptibility.
Recognizing the symptoms of multiple sclerosis
MS symptoms vary from person to person. Their severity can vary over time. The most commonly experienced MS symptoms are:
- Severe fatigue
- Inability to coordinate movements effectively
- Frequent dizziness or vertigo
- Bladder issues include frequent urination and difficulty completely emptying the bladder
- Impaired balance and coordination, which causes difficulty walking or an increased risk of falling
- Cognitive issues like difficulty thinking, remembering, concentrating, learning, and making judgments
- Mood changes, including depression, anxiety, or rapid emotional changes
- Muscle stiffness and spasms
- Pain from nerve damage
If you experience any of the following common MS symptoms, you should consult your doctor. The doctor can help you evaluate and determine the cause.
There is currently no cure for multiple sclerosis. However, the sooner it is diagnosed and treated, the better the symptoms can be managed and slow down the progression of the disease.
Have other questions about multiple sclerosis? You can make use of the consultation features that are available in the Ai Care application by downloading the Ai Care application from the App Store or Play Store.
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- Sean Edbert Lim, MBBS
John Hopkins Medicine. Multiple Sclerosis (MS). Available from: https://www.hopkinsmedicine.org/health/conditions-and-diseases/multiple-sclerosis-ms
Cleveland Clinic (2024). Multiple Sclerosis (MS). Available from: https://my.clevelandclinic.org/health/diseases/17248-multiple-sclerosis
MS Society. Early signs of MS. Available from: https://www.mssociety.org.uk/about-ms/signs-and-symptoms/early-signs-of-ms
Medline Plus (2023). Myelin. Available from: https://medlineplus.gov/ency/article/002261.htm