Lymphangioma is a benign, fluid-filled tumor often seen in children. While non-cancerous, the lymphangioma can still cause health problems depends on the size and location.
This condition arises from the lymph vessels, parts of the body’s lymphatic system. Lymphangiomas are frequently diagnosed in infants and toddlers, appearing either from birth or during the early stages of a child's development.
How Does Lymphangioma Form?
Lymphangioma is a developmental disorder within the lymphatic system, which consists of lymph vessels and nodes. This leads to fluid-filled lumps forming when there is a disruption in the development of lymph vessels during fetal growth.
In a developing fetus, lymph vessels normally connect to form a larger tissue. Lymphangiomas occur when some lymph vessels fail to join the main lymphatic system. As a result, these vessels become isolated and start to accumulate fluid, eventually forming cysts.
Lymphangiomas can increase in size over time, particularly during periods of rapid growth in children, such as infancy or puberty. In some instances, the lymphangioma may remain stable or even shrink.
Causes of Lymphangioma in Children
The exact cause of lymphangioma is not fully understood. However, abnormal development of the lymphatic system during fetal growth is a primary factor.
Incomplete development of the lymphatic system may occur in the early stages of pregnancy, around the fifth to sixth week of pregnancy. This prevents lymph vessels from properly integrating into the main lymphatic system, leading to the formation of fluid-filled cysts.
Several factors may increase the risk of lymphangioma, including:
Genetic factors and chromosomal abnormalities
Genetic factors can play a significant role in lymphangioma development. Some cases are linked to chromosomal abnormalities such as Turner syndrome, Down syndrome, and Noonan syndrome. In these conditions, genetic defects may interfere with the development of lymph vessels, leading to the formation of lymphangiomas.
Research indicates that children with chromosomal abnormalities are at a higher risk of developing lymphangiomas than those without such abnormalities.
Environmental factors and pregnancy complications
Apart from genetics, environmental conditions and complications during pregnancy may also contribute to lymphangioma. Infections during pregnancy, exposure to harmful substances, and poor maternal nutrition can all affect the development of the fetal lymphatic system.
Pregnancy complications such as premature birth or difficult labor can also increase the risk of lymphangioma. This increased risk is thought to be related to disruptions in blood flow and spleen function, although further research is needed to fully understand these connections.
Lymphangioma is often diagnosed in infants or young children. Early diagnosis is crucial to avoid complications like infection or organ dysfunction.
For more information on lymphangioma, consult your doctor or use the Ai Care health consultation service, which can be downloaded from the App Store or Play Store.
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- dr Nadia Opmalina